BDBM369720 US10233160, Compound 10::US9981925, Compound 10

SMILES COc1cc(ccc1Cl)[C@@H](CN1CCC1)Nc1nnnc2c(cccc12)C(N)=O

InChI Key InChIKey=WSHQSNODWQYJOP-MRXNPFEDSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369720   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM369720(US10233160, Compound 10 | US9981925, Compound 10)
Affinity DataIC50:  300nMAssay Description:In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM369720(US10233160, Compound 10 | US9981925, Compound 10)
Affinity DataIC50:  300nMAssay Description:In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent